Istituto di Fisiologia Clinica     
De Albuquerque Fonseca L., Picano E. Comparison of dipyridamole next term and exercise stress echocardiography for detection of coronary artery disease (a meta-analysis). In: American Journal of Cardiology, vol. 87 pp. 1193 - 1196. Elsevier Inc, 2001.
Exercise stress is the test of choice for detecting ischemic heart disease in patients who are able to exercise. However, of 5 patients we studied, 1 was unable to exercise and 1 exercised submaximally. This is one of the reasons why pharmacologic stress has become increasingly popular. Among pharmacologic stress echocardiography, dobutamine and dipyridamole are the most used and yield similar diagnostic accuracy.1 Whether dipyridamole and exercise have comparable diagnostic value remains to be assessed, because conflicting opinions2,3 have been reported in the literature. However, an opinion-based approach to the cost-sensitive issue of which test is best for diagnosis of coronary artery disease can be substantially misleading. In the present era of evidence-based medicine, meta-analysis of published trials are placed on the top of the hierarchy of evidence.4 This study assesses the relative diagnostic accuracies of dipyridamole and exercise stress echocardiography through a meta-analysis of published literature with head-tohead comparison of the 2 forms of testing on the same patient population.
URL: http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6T10-4313RG5-D-5&_cdi=4876&_user=10&_orig=search&_coverDate=05%2F15%2F2001&_sk=999129989&view=c&_alid=466704048&_rdoc=1&wchp=dGLbVlz-zSkWz&md5=97d39276d73eb5f90990d1eac2eac878&ie=/sdarticle.pdf
Subject analysis
Stress echocardiography
coronary artery disease

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