PUMA
Istituto di Fisiologia Clinica     
Quataert P., Armstrong B., Berghold A., Bianchi F., Kelly A., Marchi M., Martuzzi M., Rosano A. Methodological problems and the role of statistics in cluster response studies: A framework. In: european journal epidemiology, vol. 15 pp. 821 - 831. springer, 1999.
 
 
Abstract
(English)
More and more citizens urge public health authorities to investigate reports of disease excess in their neighbourhood. These environmental concerns are legitimate and it is part of good public health practice to respond to these complaints. However, the methodological and practical problems are severe and a lot of controversy exists about the usefulness of these investigations. To clarify the possibilities and limitations in this situation, this paper proposes a typology of cluster studies. According to this frame- work, cluster response is distinguished from two other types of cluster studies: Cluster monitoring, screening proactively for clusters to act as an early warning system, and cluster research, scrutinizing clustering to generate and test aetiological hypothe- ses. To each of these three types of cluster studies corresponds a di€erent public health context; re- spectively public health action, public health surveil- lance and public health research. Probably, part of the controversy mentioned stems from not acknowl- edging suciently the corresponding intrinsic di€er- ences in rationality and practical constraints. Cluster response is crisis management and not scienti®c re- search. In a relatively short time, an informed deci- sion should be taken by a multidisciplinary team of experts using readily available information and knowledge. In accordance with this point of view, cluster reports should be handled stepwise and the role of statistics is to quantify a cluster exploring di€erent points of view as an input to the decision process.
URL: http://www.springerlink.com/content/
Subject Birth defects


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