Istituto di Scienza e Tecnologie dell'Informazione     
Gerace I., Bedini L., Tonazzini A., Gualtieri P. Edge-preserving restoration of low-light-level microscope images. Internal note IEI-B4-25, 1994.
The low light intensity of fluorescence has always been a serious limitation to its routine use in biology and biomedicine. Since average users in digital microscopy usually posses commercial TV camera, and not sophysticated and very expensive camera, procedures for software image restoration can represent an alternative and valid solution for studying "in vivo" biological events. In this paper we present a novel algorithm for edge-preserving image restoration, and show the results of its application on a fluorescence test image. The quality of the restored image is comparable to the quality of the image acquired by a high quality camera.
Subject Fluorescences images
Markov random fields
Image restoration
Low-light-level images
I.4.4 Image Processing and computer vision. Restoration

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