Istituto di Biofisica     
Di Garbo A., Panarese A., Chillemi S. Gap junctions promote synchronous activities in a network of inhibitory interneurons. In: Biosystems, vol. 79 (1-3) pp. 91 - 99. Elsevier, 2005.
By using a single compartment biophysical model of a fast spiking interneuron the synchronization properties of a pair of cells, coupled by electrical and inhibitory synapses, are investigated. The inhibitory and excitatory synaptic couplings are modeled in order to reproduce the experimental time course of the corresponding currents. It is shown that increasing the conductance value of the electrical synapses enhances the synchronization between the spike trains of the two cells. Moreover, increasing either the decay time constant of the inhibitory current or the firing frequency of the cells favours the emergence of synchronous discharges.
DOI: 10.1016/j.biosystems.2004.09.004
Subject Synchronization
Gap junctions

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